This chapter describes Howard Andrew Knox’s childhood, education, and medical training. Knox was born on March 7, 1885, in Romeo, Michigan; he was the only child of Howard Reuben Knox and Jennie Mahaffy Knox. Knox’s parents separated when his father moved to Virginia to set up a business investing in tobacco futures. He had a close relationship with his mother that endured until her own death in 1929. In 1894, when he was just nine years old, Knox acquired a stepfather, Leander Blackwell, who was to have a decisive influence upon his choice of career. In 1899, the family moved to another farm on Babcock Hill outside Willimantic in Windham County, Connecticut. Knox settled in well at his new school, getting grades of either H (honor work) or A (excellent) in most subjects. After high school Knox entered the medical school at Dartmouth College in Hanover, New Hampshire. On March 27, 1908, Knox graduated from Dartmouth Medical School with a degree of Doctor of Medicine.
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