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The Origins of Schizophrenia$
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Alan Brown and Paul Patterson

Print publication date: 2011

Print ISBN-13: 9780231151245

Published to Columbia Scholarship Online: November 2015

DOI: 10.7312/columbia/9780231151245.001.0001

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PRINTED FROM COLUMBIA SCHOLARSHIP ONLINE (www.columbia.universitypressscholarship.com). (c) Copyright University of Minnesota Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in CUPSO for personal use.date: 25 July 2021

Maternal Infection and Schizophrenia

Maternal Infection and Schizophrenia

Chapter:
(p.25) Chapter 1 Maternal Infection and Schizophrenia
Source:
The Origins of Schizophrenia
Author(s):

Alan S. Brown

Publisher:
Columbia University Press
DOI:10.7312/columbia/9780231151245.003.0001

This chapter discusses the relationship between maternal infection and schizophrenia. Early studies of the connection between maternal infection and schizophrenia in offspring were limited by relatively imprecise definitions of the fetus' exposure to the infection. However, recent studies have proven that the exposure of an offspring to infection during pregnancy is related to schizophrenia. Among many potential infections, most ecologic studies of schizophrenia examined influenza because of its relatively high prevalence and excellent documentation in many populations, due to extensive surveillance efforts. These findings may lead to the identification of susceptibility genes that interact with these exposures. Also, it may have important implications for other practical preventive measures such as vaccination, antibiotics, and hygienic kits.

Keywords:   maternal infection, schizophrenia, offspring, fetus, genes

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