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The Origins of Schizophrenia$
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Alan Brown and Paul Patterson

Print publication date: 2011

Print ISBN-13: 9780231151245

Published to Columbia Scholarship Online: November 2015

DOI: 10.7312/columbia/9780231151245.001.0001

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Cannabis Use as a Component Cause of Schizophrenia

Cannabis Use as a Component Cause of Schizophrenia

(p.156) Chapter 6 Cannabis Use as a Component Cause of Schizophrenia
The Origins of Schizophrenia

Paola Casadio

Marta Di Forti

Robin M. Murray

Columbia University Press

This chapter studies how the use of cannabis may increase the risk of schizophrenia. Cannabis use is considered as one of the component causes in the development of psychosis. Epidemiologic studies have reported that cannabis consumption can increase the risk of having schizophrenia since tetrahydrocannabinol, the main psychoactive ingredient of cannabis, can induce psychosis. Research shows that patients suffering from schizophrenia are more likely to have used cannabis than the general population. Moreover, a dose-response relationship was observed, suggesting that heavy cannabis users were six times more likely to receive a diagnosis of schizophrenia than nonusers. Between 2002 and 2007, more studies were published that essentially substantiated the discovery.

Keywords:   cannabis, schizophrenia, tetrahydrocannabinol, psychosis, dose-response relationship

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