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The Custom-Made BrainCerebral Plasticity, Regeneration, and Enhancement$
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Pierre-Marie Lledo and Jean-Didier Vincent

Print publication date: 2014

Print ISBN-13: 9780231164504

Published to Columbia Scholarship Online: November 2015

DOI: 10.7312/columbia/9780231164504.001.0001

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PRINTED FROM COLUMBIA SCHOLARSHIP ONLINE (www.columbia.universitypressscholarship.com). (c) Copyright University of Minnesota Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in CUPSO for personal use.date: 25 September 2021

And then there was Shape

And then there was Shape

(p.19) 2 And then there was Shape
The Custom-Made Brain

Jean-Didier Vincent

Laurence Garey

Columbia University Press

This chapter discusses the development of the brain during the embryonic stage, with a particular examination on the recent discovery regarding the features of the nervous system. First, clusters of cells called morula would form the main components of the brain. The homeotic genes would then organize the precise longitudinal structure of the brain of the embryo and impose its shape. Afterwards, the neural crest would produce the bones and connective tissue of the face, with its mouth and the autonomic nervous system linking the brain to the vital organs. Research shows that these stages in the embryonic development of the brain demonstrate that the vertebrate nervous system is a mosaic. This is illustrated by the structure of the cerebral cortex, which is divided into two parts according to their phylogenetic origin: the allocortex, which represents hardly ten percent of the cortical mantle, and the neocortex, which forms most of the rest.

Keywords:   embryonic stage, morula, homeotic genes, neural crest, brain

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