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Stem Cell DialoguesA Philosophical and Scientific Inquiry Into Medical Frontiers$
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Sheldon Krimsky

Print publication date: 2015

Print ISBN-13: 9780231167482

Published to Columbia Scholarship Online: November 2015

DOI: 10.7312/columbia/9780231167482.001.0001

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PRINTED FROM COLUMBIA SCHOLARSHIP ONLINE (www.columbia.universitypressscholarship.com). (c) Copyright University of Minnesota Press, 2022. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in CUPSO for personal use.date: 01 July 2022

A Clinical Trial for Paralysis Treatment

A Clinical Trial for Paralysis Treatment

(p.181) Dialogue 25 A Clinical Trial for Paralysis Treatment
Stem Cell Dialogues

Sheldon Krimsky

Columbia University Press

This dialogue is a fictional account of science reporter Valerie Legere's interview with Dr. Fred Lincoln, a medical doctor working for Geron Corporation of Menlo Park, California. Geron was the first company in the United States to have an investigative new drug (IND) involving stem cells approved for a clinical trial on patients with acute spinal cord injury. Lincoln is overseeing the trial. Dr. Rebecca Franklin has been a short-term consultant to Geron on the ethics and science of the clinical trials because of her work on stem cells for repairing her father's spinal cord injury. Here Lincoln talks to Legere about the risks and benefits of the trial, how the trial works, the form of stem cell therapy that trial participants will receive, positive and negative outcomes expected from the trial and the precautions that Geron has been taking to prevent negative outcomes, and why the Food and Drug Administration stopped Geron's first trial in 2009.

Keywords:   investigative new drug, stem cells, spinal cord injury, ethics, clinical trials, stem cell therapy, Food and Drug Administration

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